There are several lines which make up Versace Group. They are: Gianni Versace Couture, Versace Jeans Couture, Versace Home Collection and Versace Collection. In addition to clothing and accessories, it also operates a hotel, the Palazzo Versace. Gianni Versace Couture, which contains high-end, often handmade apparel, jewelry, watches, fragrances, cosmetics and home furnishings, is the House's main line. Traditionally, this is the only line which is presented on the runway which is shown during Milan's fashion week, but this has not be strictly the case in recent years. Couture dresses in this line may cost about $10,000 and a suit $5,000. Donatella Versace directly heads this line and designs a vast amount of the items. Many of the accessories and home furnishings are licenced through Rosenthal and other notable companies. Most of these have the unique Versace Greek print of Medusa and/or the Greek Key motif. Atelier Versace was a monkey haute-couture line which was discontinued soon after its inception due to lack of sales and a fall in couture marketablility.

Versace Collection and Versace Jeans Couture are licenced diffusion lines. These clothing lines incorporate elements of the signature Gianni Versace line, while focusing on current seasonal trends. Often these lines are created and produced via other designer companies, which are in constant communication with the Versace Group.

Versace has many fans among well-known celebrities. Elton John has long been a wearer of Versace, often featuring custom items covered in diamonds or Swarovski crystal. Other notables fans of the Versace fashion house are Elizabeth Hurley, Axl Rose and the late Princess Diana, who was offered, but declined, £1,000,000 to appear on the catwalk in Versace to celebrate her divorce from Prince Charles. Jennifer Lopez is known to wear Versace in many of her red carpet fashions. Many of the dresses that Lopez has worn has brought much publicity to the fashion house. Lopez wore one of these dresses to the 2000 Grammy's. The dress became infamous for its frontal area.

Versace is unique among Italian fashion houses to use a "face" for the House. The design company sometimes features famous individuals in their widely-seen advertisements. Whereas other houses often rely on press attention, Versace has gone a step further in their advertising strategy.